Updates in Clinical Practice: New Bone Assessment Criteria
Release Date: May 25, 2016
Expiration Date: May 25, 2017
Expected time to complete this activity as designed: 15 minutes
There are no fees for participating in or receiving credit for this online activity.
The revised International Myeloma Working Group (IMWG) criteria for the diagnosis of multiple myeloma have been updated to specifically identify patients who may benefit from early treatment when prognosis is more favorable. The new criteria include myeloma-defining events in the diagnosis of active myeloma, including key changes to bone assessment criteria. Dr. Evangelos Terpos, Associate Professor of Hematology at the University of Athens School of Medicine, provides an overview of the updated criteria, focusing on the impact on bone assessments, and shares clinical expertise in choosing the best imaging technique for specific patient types and assessment goals.
This activity is designed for physicians, pharmacists, physician assistants, and other health care professionals who have an interest in enhancing their clinical skills in multiple myeloma.
Upon completion of this educational activity, participants should be able to:
- Summarize updates in the IMWG Bone Assessment Criteria in multiple myeloma
- Outline the rationale for bone assessment in patients with multiple myeloma, and the potential impact of results of these assessments on therapeutic strategies
Updates in Clinical Practice: New Bone Assessment Criteria – Evangelos Terpos, MD, PhD
Instructions for Participation and Credit
This activity is eligible for credit through May 25, 2017. After this date, this activity will expire and no further credit will be awarded.
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Evangelos Terpos, MD, PhD
Associate Professor of Hematology
Department of Clinical Therapeutics
University of Athens, School of Medicine
Dr. Evangelos Terpos is an Associate Professor of Hematology in the Department of Clinical Therapeutics, University of Athens, School of Medicine in Greece, and has been appointed as Honorary Senior Lecturer in the Department of Haematology, Faculty of Medicine Imperial College London, UK.
Dr. Terpos is co-chair of the Bone Subgroup of the International Myeloma Working Group and the Guideline Subgroup of the European Myeloma Network. He has participated in multiple myeloma (MM) clinical trials with novel antimyeloma agents and has lectured nationally and internationally on cancer-induced bone disease. Dr. Terpos has reviewed scientific papers in more than 50 medical journals, as well as abstracts for EHA and ASH meetings. In addition, he is on the editorial board of Haematologica. His main research interest is the biology of plasma cell dyscrasias, especially the biology of bone disease in MM. In more than 350 papers in peer-reviewed journals, Dr. Terpos has reported the significant role of RANKL and osteoprotegerin axis, CCL-3 (MIP-1α), Wnt and TGF-beta signaling in myeloma bone disease and cell growth. He has studied the predictive value of markers of bone remodeling and osteoclast function in myeloma progression and patients’ survival, and has evaluated the effect of bisphosphonates and different anti-myeloma therapies on bone metabolism. In addition, he has studied the biology and prevalence of osteonecrosis of the jaw in myeloma patients who receive bisphosphonates. Dr. Terpos also works on the role of modern imaging for MM, angiogenesis in MM and Waldenström’s macroglobulinemia, and renal impairment in MM.
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Dr. Evangelos Terpos has received honoraria related to formal advisory activities from Amgen Inc., Janssen Pharmaceuticals, Inc., Novartis AG, and Takeda Oncology, and the development of educational materials from Amgen and Takeda. He has received consultant fees from Amgen, Celgene Corporation, Janssen, Novartis, and Takeda, as well as grant support related to research activities from Amgen and Janssen.
Planning Committee Disclosures
The individuals listed below from MediCom Worldwide, Inc. reported the following for this activity: Joan Meyer, RN, MHA, Executive Director, has no relevant financial relationships.
Peer Reviewer Disclosure
In accordance with MediCom Worldwide, Inc. policy, all content is reviewed by external independent peer reviewers for balance, objectivity and commercial bias. The peer reviewers have no relevant financial relationships to disclose.
Off-Label Disclosures/Investigational Disclosures
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The opinions expressed in the educational activity are those of the faculty. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings. Further, attendees/participants should appraise the information presented critically and are encouraged to consult appropriate resources for any product or device mentioned in this program.
Dr. Terpos has indicated that he does not intend to discuss off-label uses of drugs, mechanical devices, biologics or diagnostics approved by the US Food and Drug Administration (FDA) for use in the US.
Dr. Terpos has indicated that he does not intend to discuss investigational drugs, mechanical devices, biologics or diagnostics not approved by the FDA for use in the US.
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This activity is supported by educational grants from Takeda Oncology and Celgene Corporation
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